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Pearl Therapeutics Inc.

This article was originally published in Start Up

Executive Summary

Drawing on a proprietary porous particle technology to create stable inhalable suspensions, Pearl Therapeutics Inc. has developed a metered-dose inhaler format able to deliver combination products across therapeutics and product types. The company's lead chronic obstructive pulmonary disease MDI candidate combines a long-acting muscarinic antagonist plus a long acting beta-2 agonist. A mid-stage clinical trial demonstrated significant benefits versus blockbuster, market-leading active comparators in patients with moderate-to-very severe COPD.

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