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How Listeria, Used as a Vaccine, Signals an Immune Response

This article was originally published in Start Up

Executive Summary

A lab at the University of California, Berkeley, has identified a small molecule that the microbe Listeria secretes while inside the host cell, which triggers a T cell response and protective immunity. The finding supports the notion that studying interactions of bacteria with the immune system could be useful in vaccine deelopment. It's also good news for the small firm re-started around the use of live, attenuated, recombinant Listeria as an adjuvant/vaccine vector.

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