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Cellular Dynamics International Inc.

This article was originally published in Start Up

Executive Summary

Cellular Dynamics International Inc. is using induced pluripotent stem (iPS) cells, derived from adult cells, as drug discovery and development tools. The company is initially pursuing the cardiotoxicity market with iCell cardiomyocytes, which closely resemble in vivo cardiomyocytes, even beating in unison in a cell culture dish. When exposed to drugs or other external agents, the cells produce electrophysiological and biochemical responses typical of in vivo cardiomyocytes.

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