Scrip is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


NKT Therapeutics Inc.

This article was originally published in Start Up

Executive Summary

In therapies that target the immune system, T cells have become an important target because of the role they play in cell-mediated immunity, directing macrophages, natural killer cells, and cytotoxic T lymphocytes towards invaders. But a subset of T cells, called natural killer T cells, may afford more precise control because they straddle both the adaptive immune system and the more generalized innate immune system that reacts more rapidly and non-specifically. NKT Therapeutics hopes to take that refinement one step further by focusing on a subset of NKT cells that don't vary from individual to individual. Moreover, the invariant T-cell receptor that they carry is identical in everyone.

You may also be interested in...

Start-Up Previews (06/2009)

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Start-Ups Set Sights on Flu," features profiles of Alios BioPharma, Immune Targeting Systems, Marinomed Biotechnologie and Vivaldi Biosciences. Plus these Start-Ups Across Health Care: CardiAQ Valve Technologies, NKT THerapeutics, SPOC Inc.,and Sutro Biopharma.

Homology Medicines Inc.

Gene editing has made a great many headlines of late, and one could be forgiven for thinking the field was saturated, but Homology Medicines Inc. offers something new. Its platform relies on a different mechanism, known as homologous recombination, and the start-up's management team believes the approach can get around some of the potential limitations found in other gene-editing technologies.


Related Companies

Related Deals




Ask The Analyst

Please Note: Click here for more information on the Ask the Analyst service.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts