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Arcion Therapeutics Inc.

This article was originally published in Start Up

Executive Summary

Arcion Therapeutics is focusing its development efforts on an existing chemical entity, clonidine, but its theory is more novel: that much or all of the abnormal pain signaling associated with neuropathic pain occurs in the skin. Thus it is trying to develop a topical form of clonidine, an alpha-2 adrenergic receptor agonist already marketed for high blood pressure. Arcion has uncovered a variety of mechanisms by which clonidine may relieve pain and hopes to soon begin a Phase IIb trial in diabetic neuropathy. The goal: a product that is easy to use and avoids many of the side effects associated with current treatments.

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Start-Up Quarterly Statistics, Q3 2009

Highlights from the Q3 2009 review of start-up dealmaking: Fundraising in the biopharma, medical device, and in vitro diagnostics industries totaled $520 million, a 40% decrease from the previous quarter and a 45% drop from Q3 2008. Of the total money raised in the current quarter, 64% or $333 million went to the biopharma companies. Compared with Q2 2009, device fundraising decreased by 76% (from $465 million to $113 million) but diagnostics companies raised significantly more--going from $23 million to $74 million. In contrast to the previous quarter, which saw only one acquisition, in Q3 2009 there were four involving start-ups, all of which are focusing on neurological disorders. On the alliance front, three companies--Oscient, NovaMed, and Ikaria Holdings--signed two deals each this quarter.

Start-Up Quarterly Statistics, Q3 2009

Highlights from the Q3 2009 review of start-up dealmaking: Fundraising in the biopharma, medical device, and in vitro diagnostics industries totaled $520 million, a 40% decrease from the previous quarter and a 45% drop from Q3 2008. Of the total money raised in the current quarter, 64% or $333 million went to the biopharma companies. Compared with Q2 2009, device fundraising decreased by 76% (from $465 million to $113 million) but diagnostics companies raised significantly more--going from $23 million to $74 million. In contrast to the previous quarter, which saw only one acquisition, in Q3 2009 there were four involving start-ups, all of which are focusing on neurological disorders. On the alliance front, three companies--Oscient, NovaMed, and Ikaria Holdings--signed two deals each this quarter.

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