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Surmises from Studying DNA Damage: A Link to Type 2 Diabetes?

This article was originally published in Start Up

Executive Summary

Researchers recently catalogued over 700 proteins associated with DNA damage and organized many of them into signaling modules. Scientists poring over this intricate data set may get insights into genetic diseases, cancer, and other complex diseases including diabetes. For example, there's a hint that long-term DNA damage affects the insulin pathway, which could revolutionize thinking about diabetes treatment by providing a set of DNA-damage-related drug targets that could stop the loss of insulin signaling and prevent the onset of the disease.

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