Translating Venture-Speak
This article was originally published in Start Up
Executive Summary
VCs are seldom forthcoming about their real reasons for rejecting a business plan. They might, for example, worry about harming a preexisting relationship; they might not want to share competitive information about another company in their portfolio; and they certainly don't want to provide a potentially embarrassing insight into the firm's internal decision-making processes. But the answers VCs give can provide useful information, if you are willing to devote the effort to translating them.You may also be interested in...
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Israeli start-up Nanolymf . believes its technology could be used to create oral versions of some of the biggest intravenous and injectable drugs on today's market, including lipophilic drugs that are not readily bioavailable because of biochemical barriers that block their absorption. Nanolymf's nanoencapsulation technology allows the drug to bypass metabolic filters in the intestine and liver, resulting in increased bioavailability following oral administration.
Why Clinical Trials Fail Unexpectedly
Is there an explanation for the recent spate of biotech Phase II and Phase III clinical trial failures?
It's almost impossible to give general reasons for specific clinical failures. Several hypotheses, borrowed from the tenets of behavioral finance, however, may help explain some recent, unanticipated later-stage setbacks. They may also support other studies that suggest that small biotech companies fail more often in clinical development than their larger biotech and pharma brethren.
Why Investors Adopt Orphans
Venture-backed biotech companies are increasingly seeking to commercialize drugs that qualify for orphan drug protection from the FDA; is this business model a good idea?
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