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Emergings in Brief (4/04)

This article was originally published in Start Up

Executive Summary

Start-Up showcases the following recently launched companies: Cira Discovery Sciences Inc., Molecular Formulations LLC, PharmaImaging Group Ltd. and Tienta Sciences Inc.

Showcasing very recently launched companies

Cira Discovery Sciences Inc.

3701 Market Street

Philadelphia PA 19104

Suite 340

Phone: (215) 966-6131

Fax: (215) 966-6001

E-Mail: [email protected]

Web Site: www.ciradiscovery.com

Management: Wade T. Rogers, PhD, President & CEO; Allan R. Moser, PhD, VP Technology; Dennis J. Underwood, PhD, Co-founder, Director & Chair, Scientific Advisory Board

Company Founded: April 2003

Financing to Date: $100,000

Investors: BioAdvance

Employees: 4

Partners/Alliances: Infinity Pharmaceuticals; The Wistar Institute

Industry Segment: Bioinformatics; Molecular Diagnostics; Services

Business: Cira Discovery applies its proprietary computational datamining technologies to its clients' drug discovery and development programs. And, in partnership with The Wistar Institute, it is using its ability to find patterns among the interactions of individual biomarkers to develop next-generation molecular diagnostic tests for lung disease and cancer.

Molecular Formulations LLC

1440 Davey Road

Woodridge, IL 60517

Phone: (630) 739-6754

Fax: (630) 972-0515

E-Mail: [email protected]

Web Site: www.molecularformulations.com

Management: Sharon W. Ayd, PhD, CEO

Company Founded: January 2004

Financing to Date: Undisclosed seed round

Investors: Flavin Ventures LLC

Employees: 5

Partners/Alliances: Shamrock Structures LLC; Advanced Life Sciences Inc.

Industry Segment: Services

Business: By identifying optimal formulation features early in the drug development process, Molecular Formulations hopes to increase the efficiency of its pharma and biotech clients' downstream clinical development activities. The start-up will offer a broad range of services, from physiochemical characterization of hits through prototype development and stability studies.

PharmaImaging Group Ltd.

Chambers Building

Earls Road

Grangemouth FK3 8XG, Scotland, UK

Phone: (44) 1324 494360

Fax: (44) 1324 494596

E-Mail: [email protected]

Web Site: www.pharmaimaging.com

Management: Keith McKellar, CEO; Dr. Bernard Ayton, Commercial Director; Brian Williamson, Finance Director

Company Founded: October 2003

Financing to Date: £15 million ($27.4 million)

Investors: Schering Health Care Ltd.; GE Medical Systems; Knight Real Estate; Scottish Executive (through RSA); Scottish Enterprise; Private investors

Employees: 15

Partners/Alliances: GE Medical Systems

Industry Segment: Clinical Research Services; Diagnostics

Business: Scotland's biggest corporate start-up in the last 30 years, PharmaImaging's goal is to become Europe's most advanced pharmaceutical imaging center. It will provide gamma scintigraphy to assist clients with drugs in early clinical development from the second quarter 2004, followed by PET, MRI and ultrasound in early 2005. Medical imaging services for patients will also be available in the first quarter of 2005.

Tienta Sciences Inc.

351 West 10th Street

Suite 352

Indianapolis, IN 46202

Phone: (317) 278-6113

Fax: (317) 278-8190

E-Mail: [email protected]

Web Site: www.tientasciences.com

Management: Mike Treble, Co-founder & CEO; Raymond DeGrella, PhD, VP R&D David Kolasinksi, Co-founder & VP; Anthony J. Hubbard, VP & CFO; John G. R. Hurrell, PhD, Co-founder & Chairman

Company Founded: October 2003

Financing to Date: Undisclosed

Investors: Inproteo Inc.

Employees: 4.5

Partners/Alliances: Inproteo Inc.; Jobin Yvon Inc.; Purdue University

Industry Segment: Drug Discovery Tools

Business: Tienta Sciences is the first spin-out of Inproteo Inc., the joint venture between Eli Lilly & Co. , Purdue University , and Indiana University . Tienta's proprietary SpectRIM sample substrate technology is designed to increase the sensitivity and utility of Raman, infrared, and mass spectrometry for protein discovery and analysis, and should enable researchers to 'fingerprint' molecules to identify subtle changes in protein structure that other analysis methods can't detect.

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