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Norak Biosciences Inc.

This article was originally published in Start Up

Executive Summary

Norak's founders think that beta-arrestin's movement from within the body of the cell to the membrane-bound receptor is a specific marker of GPCR receptor activation-and their method for watching it all happen in glowing green is the basis of the company's Transfluor technology.

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Faust Pharmaceuticals

Strasbourg, France-based Faust Pharmaceuticals aims to identify and develop small molecule drug candidates that can modulate the level of neurotransmitters in the brain to treat neurodegenerative disorders including Parkinson's Disease and Alzheimer's Disease.

Axovan Ltd.

Using proprietary high-throughput screening techniques, Axovan is now identifying compounds that bind to GPCRs with high affinity. It reduces screening time by taking into account the homology between receptors, which enables it to screen up to eight receptors in parallel: the company claims to be the only one able to screen up to 30 GPCR receptors per year.

7TM Pharma

7TM Pharma aims to apply proprietary functional and structural knowledge of 7TM receptors to aid in the design of small-molecule therapeutics, and hopes to succeed commercially by choosing a specific therapeutic area-metabolic diseases, and in particular, obesity-on which to apply its technology.

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