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Study: Protein Mutation Protects Indian HIV Patients From AIDS Dementia

This article was originally published in PharmAsia News

Executive Summary

A research team has determined India has a relatively low incidence of AIDS-induced dementia because of a mutation that occurs in Indian patients. Four percent of Indians infected with HIV get AIDS-induced dementia, while 45 percent of HIV patients in the West get the dementia, the study determined. Researchers ascribed the difference to Tat, a neuro-toxic protein in the AIDS virus that mutates naturally. The Indian strain, HIV1-C is the only strain of 10 that undergoes the mutation that leads to Tat being ineffective in Indians infected with HIV. (Click here for more

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