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Prothena spikes on Phase I Parkinson's data

This article was originally published in Scrip

Executive Summary

Shares in Elan spin-out Prothena shot up by as much as 37% to $40.14 on Nasdaq on 20 March on the back of Phase I data for its experimental Parkinson's disease therapy PRX002. The monoclonal antibody product is being developed under a worldwide collaboration with Roche for antibodies targeting alpha-synuclein that was signed in late 2013. PRX002 was safe and well-tolerated, meeting the primary objective of the study, and further results showed that administration of PRX002 led to rapid and dose-dependent reductions of free serum alpha-synuclein levels of up to 96% (p<0.00001).>



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