INFOGRAPHIC: PCSK9 inhibitors alirocumab and evolocumab side-by-side
This article was originally published in Scrip
Executive Summary
Clinical trial results to date for the PCSK9 inhibitors evolocumab from Amgen and alirocumab from Sanofi and Regeneron Pharmaceuticals have been quite similar in patients with hypercholesterolemia, or high cholesterol, across several studies even though no two study designs are exactly alike.
You may also be interested in...
Finance Watch: Canaan, Regeneron Reveal New Funds For Start-Ups
Private Company Edition: Regeneron launched a $500m venture fund and Canaan added $100m, bringing the venture firm’s recent total to $1bn-plus. Also, incubators plan to grow over the next decade and in recent financings Avenzo raised $150m and Nvelop launched with $100m.
Sage’s Dalzanemdor Prospects In Doubt After First Mid-Stage Readout
Dalzanemdor (SAGE-718) showed no difference from placebo in a Phase II Parkinson’s disease study, raising concerns about readouts later this year in Huntington’s and Alzheimer’s diseases.
First Phase III Depression Data For Intra-Cellular’s Caplyta Exceed Expectations
With positive results from the first Phase III trial of lumateperone in major depressive disorder and a second readout expected later this quarter, the company plans a supplemental filing in late 2024.