Gilead's HIV franchise looks secure as 'son of Viread' impresses in PhIII
This article was originally published in Scrip
Two Phase III trials of Gilead Sciences' once-daily tablet containing its next-generation Viread product, tenofovir alafenamide (TAF), have met their primary objectives. The data are expected to help Gilead fight off generic competition to its hugely successful HIV franchise.
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Company hopes TAF-based combo incorporating integrase inhibitor bictegravir can help it compete with ViiV, but beyond that pipeline holds only early-stage and smaller opportunities in HIV. Analysts call on Gilead to use its cash stockpile to find its next R&D focus.
Eighty percent of patients who’ve received Genvoya so far are switched over from older Gilead regimens, while 10% have switched from non-Gilead drugs. In terms of cumulative prescriptions, the Genvoya launch is outpacing the launch of predecessor drug Stribild to date.
The UK's main reimbursement bodies made a series of decisions this week that were broadly favorable and largely focused on oncology medicines.