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GlaxoSmithKline's Phase III COMBI-v study of its MEK inhibitor, Mekinist (trametinib), in combination with its BRAF inhibitor, Tafinlar (dabrafenib), compared with Roche's Zelboraf (vemurafenib) in patients with BRAF V600E or V600K mutation-positive unresectable or metastatic cutaneous melanoma has been stopped early.
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