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Novartis follows Roche's Erivedge with hedgehog basal cell carcinoma success

This article was originally published in Scrip

Executive Summary

Novartis is to discuss with regulators the results of a Phase II study of its investigational oral product LDE225 (sonidegib) in advanced basal cell carcinoma after a significant tumor response rate was seen in the trial. The product, which acts on the hedgehog pathway, is already in Phase III trials for brain cancer (relapsed medulloblastoma).

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