Arena moves PAH drug forward despite Phase Ib adverse event
This article was originally published in Scrip
Executive Summary
Arena Pharmaceuticals is moving ahead with a Phase II clinical trial for its pulmonary arterial hypertension (PAH) drug APD811 based on data from two Phase I trials, including an incidence of transient atrial fibrillation that may have been caused by the company's oral prostacyclin (IP) receptor agonist.
You may also be interested in...
Arena Rises, But Raises Questions With Phase II Ralinepag Data In PAH
Arena reported statistically and "clinically" significant results from its Phase II study for ralinepag in pulmonary arterial hypertension (PAH), driving its share price up by more than 40%, but details expected later this year or in 2018 are needed to shed more light on the data.
Italfarmaco To Seek Givinostat Approvals After Phase III Success In DMD
Italfarmaco’s HDAC inhibitor helped ambulatory Duchenne muscular dystrophy patients climb stairs faster than non-treated boys while Capricor’s cell therapy improved upper limb function in non-ambulatory patients.
Finance Watch: Venture Floodgates Open With New Funds, Dozens Of Rounds
Private Company Edition: While the tough state of financing for publicly traded drug developers continues, venture capital firms and private biopharma companies revealed billions of dollars in new VC funds and start-up financings, including $100m-plus mega-rounds for Tessa, Alladapt and ImCheck.