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J&J set to exploit diabetes drug safety scare

This article was originally published in Scrip

Executive Summary

With its 29 March PDUFA date almost upon us, J&J's SGLT2 inhibitor Invokana (canagliflozin) is ready to exploit the latest concerns of a potential increased risk of pancreatitis and precancerous cellular changes in patients with type 2 diabetes treated with glucagon-like peptide-1 (GLP-1) agonists and dipeptidylpeptidase-4 (DPP-4) inhibitors (scripintelligence.com, 26 March 2013).

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