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Alexza's Adasuve crosses US finish line, but distribution limited

This article was originally published in Scrip

Executive Summary

Right on schedule, Alexza Pharmaceuticals won a late-afternoon US approval on 21 December to market its inhaled antipsychotic Adasuve (loxapine) to treat agitation associated with schizophrenia or bipolar I disorder in adults, although the drug came with and a black-box warning and must be dispensed through a restricted distribution program, which likely was the trigger for the sell-off of the firm's shares.


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