GSK and Janssen wade into competitive RA market with Phase III sirukumab program
This article was originally published in Scrip
Executive Summary
GlaxoSmithKline and Janssen Biologics kicked off the Phase III program for their interleukin-6 (IL-6) inhibitor sirukumab (CNTO 136), which would compete with relative newcomers in the competitive rheumatoid arthritis market – Genentech's Actemra (tocilizumab), the first IL-6 inhibitor approved to treat patients with moderately to severely active rheumatoid arthritis, and Pfizer's novel oral Janus kinase (JAK) inhibitor tofacitinib.
You may also be interested in...
Ipsen Expands Its Rare Neurological Disease Pipeline With Skyhawk Deal
Deal Snapshot: Ipsen committed up to $1.8bn in upfront and milestone fees to develop novel treatments for rare neurological diseases with Skyhawk’s RNA-targeting small molecule platform.
Finance Watch: Canaan, Regeneron Reveal New Funds For Start-Ups
Private Company Edition: Regeneron launched a $500m venture fund and Canaan added $100m, bringing the venture firm’s recent total to $1bn-plus. Also, incubators plan to grow over the next decade and in recent financings Avenzo raised $150m and Nvelop launched with $100m.
Sage’s Dalzanemdor Prospects In Doubt After First Mid-Stage Readout
Dalzanemdor (SAGE-718) showed no difference from placebo in a Phase II Parkinson’s disease study, raising concerns about readouts later this year in Huntington’s and Alzheimer’s diseases.