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NICE says no to GSK's Tyverb and Roche's Herceptin, again

This article was originally published in Scrip

Executive Summary

Neither GlaxoSmithKline's Tyverb (lapatinib) nor Roche's Herceptin (trastuzumab) represent value for money when used alongside aromatase inhibitors for treating postmenopausal women with metastatic hormone-receptor-positive breast cancer that overexpresses HER2, says NICE, the health technology appraisal institute for England and Wales. The institute also has doubts about whether the drugs improve overall survival compared to existing treatments, according to today's final draft guidance.

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