Scrip is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


Satori pins Alzheimer's hopes on selectively modulating gamma secretase; gains $15M funding

This article was originally published in Scrip

Executive Summary

Satori Pharmaceuticals, a US company founded in 2005, raised $15 million in an insider round to fund the development of selective modulators of gamma secretase that might slow or stop the progression of plaque build-up in Alzheimer's disease. Gamma secretase was the target of Eli Lilly's ill-fated Alzheimer drug semagacestat, an inhibitor of the enzyme, and of other now-withdrawn inhibitors. However, Satori believes that modulation of the enzyme rather than outright inhibition can avoid the toxic impact that caused Lilly to curtail semagacestat's development.


Related Companies




Ask The Analyst

Please Note: Click here for more information on the Ask the Analyst service.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts