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Bayer must convince NICE it has not overestimated the effectiveness of Xarelto

This article was originally published in Scrip

Executive Summary

Bayer must convince NICE, the health technology appraisal institute for England and Wales, of the relative effectiveness of its oral anticoagulant Xarelto (rivaroxaban) before it can win a recommendation for preventing stroke and systemic embolism in atrial fibrillation patients. According to preliminary NICE draft guidance, the company may have overestimated the drug's relative effectiveness compared to long-time standard of care, warfarin.



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