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AVEO/Astellas 2012 filing for tivozanib as it beats Nexavar in Ph III kidney cancer trial

This article was originally published in Scrip

Executive Summary

Tivozanib, AVEO Pharmaceuticals' VEGF inhibitor partnered with Astellas Pharma, was better than Bayer HealthCare/ Onyx Pharmaceuticals ' Nexavar (sorafenib) in prolonging progression-free survival in patients with advanced renal cell carcinoma (RCC) in a Phase III head-to-head study, top-line data show. AVEO and Astellas said the trial results mean they will submit the drug for marketing approval in the US and Europe this year.

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