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Isis's new approach to cardiovascular disease shows early promise

This article was originally published in Scrip

Executive Summary

Isis Pharmaceuticals is planning to conduct a Phase II proof-of-concept study next year, evaluating the efficacy of its candidate cardiovascular therapeutic, ISIS-APOCIIIRx, after the product was found to lower levels of apolipoprotein C-III (apoC-III) protein and triglycerides in a Phase I trial.

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