Knopp's dexpramipexole shows Phase II benefit in ALS
This article was originally published in Scrip
Knopp Biosciences has published a Phase II study of dexpramipexole, a small-molecule modulator of mitochondrial bioenergetics, in patients with amyotrophic lateral sclerosis (ALS), in which researchers said that they had "detected an apparent clinically significant, dose-dependent effect on both function and mortality". The data also suggest that the drug may slow down the decline in the disease.
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