Phase II data raise licensing hope for Targacept's TC-5619
This article was originally published in Scrip
Executive Summary
Targacept has reported encouraging top-line results from a Phase II trial with TC-5619 that could trigger an upfront payment of $30 million from AstraZeneca, plus further milestone and royalty payments, should AstraZeneca decide to take up an option on the schizophrenia compound.
You may also be interested in...
All The Way To The Top: Diversity And Inclusion In Pharma Leadership
Policies, programs and strategies promoting diversity and inclusion are almost as ubiquitous in the pharmaceutical industry these days as environmental commitments. That reflects enormous cultural change over the last few generations, hastened in recent history by initiatives such as MeToo or Black Lives Matter.
HemaQuest expands Phase II remit for HQK-1001 in sickle cell disease
HemaQuest, a US biotech focused on developing small-molecule therapeutics for haemoglobin diseases, has expanded the Phase II programme for its lead compound, HQK-1001, in sickle cell disease with a new trial aimed at establishing safety and tolerability at higher dose levels and over a longer course of therapy.
Novartis withdraws European application for 'personalised' lumiracoxib
Novartis' efforts to revive its COX-2 inhibitor lumiracoxib under a new brand name, and with the risk of hepatotoxicity that killed the drug in its original incarnation muted by a companion diagnostic, have stumbled in Europe after the company withdrew an application for centralised approval of what is now known as Joicela.