2011 Scrip 100: Fine-tuning the epigenetic ecosystem
This article was originally published in Scrip
Executive Summary
Ten years on and the human genome has turned out not to be quite as useful as was once hoped it might be. We didn't know that then, of course. In the deep barren void of 1990s human biology, any dim glimmer appears to bathe every question in light. What the human genome sequence and its variation among individuals demonstrated all too clearly in a Rumsfeldian manner, is that there are more ways of not knowing about human health and disease than anyone could have imagined a decade ago.