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NICE U-turn on Alzheimer's guidance

This article was originally published in Scrip

Executive Summary

NICE has today backtracked on earlier controversial guidance rejecting Pfizer/Eisai's Aricept (donepezil), Shire's Reminyl (galantamine) and Novartis's Exelon (rivastigmine) for treating patients with mild Alzheimer's disease as well as Lunbeck's Ebixa (memantine) for severe disease. Some new evidence and a new economic model looking at the cost-effectiveness of acetylcholinesterase (AChE) inhibitors are key to the change of heart.



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