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Roche/Ipsen suspend pivotal taspoglutide trials

This article was originally published in Scrip

Executive Summary

Roche and Ipsen have stopped dosing patients in pivotal trials of their GLP-1 analogue taspoglutide, following high patient drop-out rates owing to gastrointestinal tolerability and hypersensitivity reactions. The news – which comes a few months after the companies first disclosed the unexpected hypersensitivity and anaphylactic reactions associated with the injection – has fuelled speculation that the end may be near for the experimental antidiabetic.



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