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Amgen's Vectibix yields mixed results in second-line Phase III colorectal cancer trial

This article was originally published in Scrip

Executive Summary

Amgen's EGFR-targeted human monoclonal antibody, Vectibix (panitumumab), met one of its co-primary endpoints, progression-free survival (PFS), but not the other, overall survival, in patients with KRAS wild-type metastatic colorectal cancer (mCRC) in the pivotal Phase III "181" trial testing it as second-line therapy.



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