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Kidney disease targeted by Noxxon's mirror-image oligonucleotides

This article was originally published in Scrip

Executive Summary

Noxxon Pharma has started its first clinical study with its "Spiegelmer" compounds. These are mirror-image oligonucleotides (L-aptamers) which are not metabolised and do not interact with normal nucleic acids, but do bind to pharmacologically active target molecules.

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