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Once-weekly Byetta shows superiorty over oral antidiabetics in Phase III

This article was originally published in Scrip

Executive Summary

Lilly/ Amylin's once-weekly version of the twice-daily injectable diabetes drug Byetta (exenatide), a GLP-1 analogue, has been shown in a Phase III trial to provide improved glucose control and weight loss than two oral antidiabetics, Merck & Co's DPP-4 inhibitor Januvia (sitagliptin) and Takeda's thiazolidinedione Actos (pioglitazone), in patients with type 2 diabetes who were inadequately controlled on metformin.



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