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Study backs gene therapy for heart failure:

This article was originally published in Clinica

Executive Summary

Collateral Therapeutics' angiogenesis-promoting gene has shown promise as a non-surgical treatment for heart failure, according to results from a placebo-controlled animal study in the March issue of Cardiac and Vascular Regeneration. Intracoronary delivery of the company's human gene fibroblast growth factor-4 (FGF-4) increased heart function and reduced the size of dilated hearts over the three-week study period. The San Diego, California-based company has licensed the gene exclusively from New York University. Collateral is also using the FGF-4 gene to develop a treatment for coronary artery disease.

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